Researchers at MIT and women’s Hospital have developed a capsule that can have a week quantity of HIV drugs in just one dose. This advanced step could make it easier for patients to follow the inflexible schedule of the required amount of drugs that contain a mix of medications to fight the virus.
This new capsule is shaped for patients to take it just once a week, and the drug will loose little by little throughout the week.
This kind of delivery method could not only enhance patients’ commitment to their treatment plan but also be used by people at risk of HIV exposure to help stop them from getting infected, the researchers say.
“one of the main barriers to treating and preventing HIV is adherence” says Giovanni Traverso, a researcher affiliate at MIT’s Koch Institute for Integrative Cancer Research and gastroenterologist and biomedical engineer at Brigham and women’s Hospital.
“The ability to make doses less frequent stands to improve adherence and make a significant impact at the patient level.”
Traverso and Robert Langer, the David H. Koch Institute Professor at MIT, are the senior authors of the study, which appears in the Jan. 9 issue of Nature Communications. MIT Postdoc Ameya Kirtane and visiting scholar Omar Abouzid are the lead authors of the document.
Scientists from Lyndra, a corporation that was lunched to expand this technology, helped in this research. Lyndra is right now acting some clinical trials by this delivery system.
“We are all very excited about how this new drug-delivery system can potentially help patients with HIV/AIDS, as well as many other diseases” Langer says.